Human-Derived Plasma Ancillary Materials for Cell Therapies: What Virus Inactivation Methods Should You Consider?

Human plasma is defined as “clear, straw colored, complex liquid that is 7% protein, 91% water, and 0.9% mineral salts” and can be derived from Source or Recovered Plasma. Today, human plasma is used to produce several ancillary materials such as Human AB Serum, Human Fibronectin, Human Serum Albumin (HSA), and Human Vitronectin. These materials

Fibronectin and BMP act in synergy to improve osteogenic activity

Fibronectin is well-known as an attachment extracellular matrix (ECM) protein that promotes activity, including differentiation, of a number of cell types. It has also been used in a number of tissue engineered constructs to enhance their function as well as cellular proliferation. As a workhorse ECM protein, fibronectin’s use is well-established in many tissue engineering