Akron Participates in Newly Published Study Modelling Cost of Goods for Allogeneic CAR T

Cell and gene therapies have demonstrated excellent clinical results across a range of indications with chimeric antigen receptor (CAR)–T cell therapies among the first to reach market. Although these therapies are currently manufactured using patient-derived cells, therapies using healthy donor cells are in development, potentially offering avenues toward process improvement and patient access. An allogeneic

Upcoming Events – September 2018

As a scorching summer draws to a close and conference season begins, Akron will be participating at many upcoming events to further advocate for the use of higher quality ancillary materials in regenerative medicine processes.  Our focus of providing affordable cGMP reagents throughout the development stages for these unique therapeutics serves to better ensure reproducibility

Macrophages derived from stem cells help mice to breathe again

Hereditary pulmonary alveolar proteinosis (herPAP) is a rare life-threatening disease characterized by the slow accumulation of lipoproteins in the lungs. Surfactant and other lipoproteins are typically cleared from alveoli by a specialized group of cells called alveolar macrophages that require the signaling molecule termed granulocyte macrophage colony-stimulating growth factor (GM-CSF) to maintain normal surfactant levels.

Innate Killer Summit 2018 presents cutting-edge innovations and the latest clinical data for NK cell therapies

Akron Biotech was proud to be a sponsor of this year’s Innate Killer Summit held in San Diego, California. The Innate Killer Summit is the leading, dedicated end-to-end meeting serving as a catalyst to ensure successful clinical and commercial translation of NK cell immunotherapies. The most current and advanced clinical data was presented as well

First allogeneic stem cell therapy approved in Europe

TiGenix and Takeda announced that the European Commission (EC) has approved Alofisel (darvadstrocel) for the treatment of complex perianal fistulas in adult patients with nonactive/mildly active luminal Crohn’s disease, marking the first allogeneic stem cell therapy to receive central marketing authorization approval in Europe. Crohn’s disease is a chronic condition that causes intestinal inflammation. A

Synthetic IL-2 cytokine-receptor pairs enable selective targeting of engineered T cells

Interleukin-2 (IL-2) is a cytokine critical to effector T cell expansion, survival, and function. Importantly, IL-2 is supplemented in the production of T cells for immunotherapy, including CAR-T cell therapies. While IL-2 can improve T cell survival and efficacy, IL-2 provokes a wide range of responses by simultaneously activating and repressing different components of the

Akron CEO Zylberberg interviewed for the Innate Killer Summit 2018

The Innate Killer Summit is the leading, dedicated end-to-end meeting serving as the catalyst to ensure successful clinical and commercial translation of Natural Killer (NK) cell immunotherapies. Leading up to the March 2018 event in San Diego, CA, Akron Biotechnology CEO Claudia Zylberberg, Ph.D. shared some key issues and questions arising in the NK therapy

Forum on Regenerative Medicine at the National Academies Releases Perspective Paper on Cell Therapy Manufacturing

The Forum on Regenerative Medicine at the National Academies of Science, Engineering and Medicine released today a perspective discussion paper on cell therapy manufacturing. The discussion paper, titled “Manufacturing Cell Therapies: The Paradigm Shift in Health Care of This Century,” can be accessed through the National Academy of Medicine perspectives page. It discusses challenges, issues