Recombinant Human CD40 Ligand/CD154, rHu CD40-L
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CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen that is expressed on the surface of T cells.
- Animal-Free protein
- Certificate of Analysis included with each order
- Lot-specific: SDS-PAGE, LAL analysis, and bioactivity
- Purity levels are 95% or greater
- Custom packaging for bulk orders
The CD40-L stimulates both B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. It has been shown that CD40-L induces cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T-cells, which is accompanied by the production of IFN-γ, TNF-α, and IL-2. Recombinant human CD40-L is a non-glycosylated protein, made up of 149 amino acids and with a molecular mass of 16.3 kDa.
1 mg, 10 μg, 100 μg, 50 μg