Recombinant Human CD40 Ligand/CD154, rHu CD40-L

Recombinant Human CD40 Ligand/CD154, rHu CD40-L

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CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen that is expressed on the surface of T cells.

  • Animal-Free protein
  • Certificate of Analysis included with each order
  • Lot-specific:  SDS-PAGE, LAL analysis, and bioactivity
  • Purity levels are 95% or greater
  • Custom packaging for bulk orders

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SKU: AK9162
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The CD40-L stimulates both B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. It has been shown that CD40-L induces cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T-cells, which is accompanied by the production of IFN-γ, TNF-α, and IL-2. Recombinant human CD40-L is a non-glycosylated protein, made up of 149 amino acids and with a molecular mass of 16.3 kDa.

Size

1 mg, 10 μg, 100 μg, 50 μg