cGMP Recombinant Human Interleukin-2, rHu IL-2

cGMP Recombinant Human Interleukin-2, rHu IL-2

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Akron’s industry-leading IL-2 is produced under stringent cGMP guidelines in a variety of ready-to-use configurations.

Interleukin-2 promotes the growth and activity of T and B lymphocytes, and is key in a number of cell and cell-based gene therapies.

Features and Specifications:

  • Available as 10µg, 100µg, and 1mg
  • Source: E. Coli
  • Identical amino acid sequence to aldesleukin (Proleukin®)
  • Animal component free
  • Defined functionally based on biological assays
  • Sterile lyophilized and filled
  • Sterility & endotoxin-tested according to USP
  • 24 months stability
  • Storage: 2-8°C
  • Custom biologic activity assay available upon request
  • DMF (eCTD format) Available

To request availability, pricing, or a letter of authorization for your fillings, please contact

Quality Statement

Akron’s cGMP Cytokines are manufactured, tested and released in compliance with relevant cGMP guidelines. USP Chapter ‹1043› “Ancillary materials for cell, gene and tissue-engineered products” has been followed in the design of these products.

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IL-2 signals through the IL-2R receptor in order to induce the proliferation of activated T cells. IL-2 also stimulates proliferation and differentiation of B cells, natural killer cells, monocytes and macrophages. Recombinant human IL-2 produced in E. coli is a non-glycosylated protein with a molecular weight of approximately 15.3 kDa. The recombinant sequence differs from native interleukin-2 in the following ways: a) the molecule has no N-terminal alanine; and b) the molecule has serine substituted for cysteine at amino acid position 125.

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