cGMP Recombinant Human Interleukin-2, rHu IL-2

cGMP Recombinant Human Interleukin-2, rHu IL-2

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Interleukin-2 (IL-2) is an immuno-modulatory cytokine produced by stimulated T-cells. Akron’s industry-leading IL-2 is produced under stringent cGMP guidelines in a variety of ready-to-use configurations.

Features and Specifications:

  • Custom packaging and sizes available
  • Single-use syringe configuration
  • Lyophilized or liquid format
  • Pharmaceutical grade
  • Sterile-filled
  • Custom biological activity assays available
  • Drug Master File available (# 030268)

 

Quality Statement

Akron’s cGMP Cytokines are manufactured, tested and released in compliance with relevant cGMP guidelines. USP Chapter ‹1043› “Ancillary materials for cell, gene and tissue-engineered products” has been followed in the design of these products.


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IL-2 signals through the IL-2R receptor in order to induce the proliferation of activated T cells. IL-2 also stimulates proliferation and differentiation of B cells, natural killer cells, monocytes and macrophages. Recombinant human IL-2 produced in E. coli is a non-glycosylated protein with a molecular weight of approximately 15.3 kDa. The recombinant sequence differs from native interleukin-2 in the following ways: a) the molecule has no N-terminal alanine; and b) the molecule has serine substituted for cysteine at amino acid position 125.

Interleukin 2 Size

1 mg

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