cGMP Recombinant Human Interleukin-2, rHu IL-2

cGMP Recombinant Human Interleukin-2, rHu IL-2

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Akron’s industry-leading IL-2 is produced under stringent cGMP guidelines in a variety of ready-to-use configurations.

Interleukin-2 promotes the growth and activity of T and B lymphocytes, and is key in a number of cell and cell-based gene therapies.

Features and Specifications:

  • Available as 10µg, 100µg, and 1mg
  • Source: E. Coli
  • Identical amino acid sequence to aldesleukin (Proleukin®)
  • Animal component free
  • Defined functionally based on biological assays
  • Sterile lyophilized and filled
  • Sterility & endotoxin-tested according to USP
  • 24 months stability
  • Storage: 2-8°C
  • Custom biologic activity assay available upon request
  • DMF (eCTD format) Available

To request availability, pricing, or a letter of authorization for your fillings, please contact sales@akronbiotech.com.

Quality Statement

Akron’s cGMP Cytokines are manufactured, tested and released in compliance with relevant cGMP guidelines. USP Chapter ‹1043› “Ancillary materials for cell, gene and tissue-engineered products” has been followed in the design of these products.


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IL-2 signals through the IL-2R receptor in order to induce the proliferation of activated T cells. IL-2 also stimulates proliferation and differentiation of B cells, natural killer cells, monocytes and macrophages. Recombinant human IL-2 produced in E. coli is a non-glycosylated protein with a molecular weight of approximately 15.3 kDa. The recombinant sequence differs from native interleukin-2 in the following ways: a) the molecule has no N-terminal alanine; and b) the molecule has serine substituted for cysteine at amino acid position 125.

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