cGMP Human Fibronectin

cGMP Human Fibronectin

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Fibronectin is an attachment factor that facilitates the attachment and cytoplasmic spreading of all types of anchorage-dependent cells.

Features and Specifications:

  • Concentration: 1mg/mL
  • Bioassay qualified
  • Origin:   Human plasma from U.S. donors 
  • Plasma units were collected in US licensed plasma donation centers and were viral tested as per 21 CFR 610.40 at the time of collection.  All units have been tested and found negative for HAV, HBV, HCV and HIV. 
  • Pooled plasma was tested and found negative for HBsAg, HIV-1/2 antibodies, and HAV, HBV, HCV, and HIV (PCR).
  • cGMP product includes Mycoplasma, Endotoxin, and Sterility testing.
  • For research and further manufacturing use only. Not for human use.
  • Custom packaging available for contract orders

Quality Statement

Akron’s cGMP Products are manufactured, tested and released in compliance with relevant cGMP guidelines. USP Chapter ‹1043› “Ancillary materials for cell, gene and tissue-engineered products” has been followed in the design of these products.


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Fibronectin is responsible for cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis.

Applications:

  • Promote cell-substrate attachment
  • Improve cellular differentiation
  • Reduce variation in plating efficiency found in different serum batches

Plasma-Derived Fibronectin

Plasma fibronectin (pFN) is secreted by hepatocytes as a major protein component of blood. pFN opsonizes bacteria and helps form clots. Plasma FN is widely used in cell culture to help cells attach to the substrate. It is particularly useful for culturing cells that are incapable of synthesizing their own biomatrix, including stem cells, and for culturing cells in serum-free medium. Akron’s pFN is a clear, sterile, buffered solution with a pH of about 7.0 to 8.0.

 

Fibronectin Size

Cell Derived 1 ml, Cell Derived 5 ml, GMP Plasma Derived, GMP Plasma Derived Viral Inactivated, Plasma Derived 1 ml, Plasma Derived 5 ml