DMSO-Free Cryopreservation

Novel biomaterials avoid deficiencies of DMSO, while retaining cell and tissue viability and functionality.

Cryopreservation of cells is as much about freezing, as it is about bringing back to life. Cells undergo damage during cryopreservation which includes, but is not limited to, ice crystal formation and cryoinjury. These are undesirable as functionality is affected.

Traditionally, stem cell cryopreservation has employed the use of DMSO, which has increasingly been linked to complications post-transplantation.

With new discoveries and developments in biomaterials, a better understanding of cell biophysics and the interaction between cells and cryoprotective properties of DMSO-free materials, we are leading the innovation in safe, naturally-occurring and xeno-free DMSO-free cryoprotectants.

From cell to bioengineered tissue cryopreservation, we are continuously developing new solutions to improve one of the critical elements of cell and gene therapies.

icecubec

DMSO-free highlights

  • Bioinspired biomaterials
  • Cryodamage reduction or avoidance
  • Cell functionality maintained
  • Tissue and organ cryopreservation